Réseau en Santé Respiratoire du Québec
Un levier pour la recherche au Québec
Biobanque
A large lung gene expression study identifying fibulin-5 as a novel player in tissue repair in COPD
CA Brandsma, M Berge, D S Postma, M R Jonker, S Brouwer, P D Paré, D D Sin, Y Bossé, M Laviolette, J Karjalainen, R S N Fehrmann, D C Nickle, e Hao, A I R Spanjer, W Timens, L Franke
Thorax,
2014, 70:21-32 doi:10.1136/thoraxjnl-2014-205091
Alveolar macrophage subpopulations in bronchoalveolar lavage and induced sputum of asthmatic and control subjects
J St-Laurent, V Turmel, LP Boulet, E Bissonnette
J Asthma,
2009, Feb;46(1):1-8.
Alveolar macrophages in allergic asthma: An expression signature characterized by heat shock protein pathways.
A-M Madore, S Perron, V Turmel, M Laviolette, EY Bissonnette, C Laprise.
Hum Imm,
2010, Feb;71(2):144-150. Epub 2009 Nov 12.
Bronchodilatory and Anti-Inflammatory Effects of ASM-024, a Nicotinic Receptor Ligand, Developed for the Treatment of Asthma
E Israël-Assayag , M-J Beaulieu, Y Cormier
PLoS ONE,
2014, Mar 23;10(3):e0120095. doi: 10.1371/journal.pone.0120095. eCollection 2015
Deleterious impact of Pseudomonas aeruginosa on cystic fibrosis transmembrane conductance regulator function in airway epithelial cells
NT Nguyen Thu Ngan Trinh, N.Trinh, C.Bilodeau, E. Maillé, M. Ruffin, M-C Quintal, M-Y Desrosiers,S.Rousseau, E.Brochiero
Eur Resp J,
2015, Mar 18. pii: ERJ-00762-2014
Differences in airway cytokine profile in severe asthma compared to moderate asthma.
J Shannon, P Ernst, Y Yamauchi, R Olivenstein, C Lemiere, S Foley, L Cicora, M Ludwig, Q Hamid, JG Martin
Chest,
2008, Feb;133(2):420-6
Dissecting the genetics of chronic mucus hypersecretion in smokers with and without COPD
AE Dijkstra , HM Boezen HM, M van den Berge, JM Vonk, PS Hiemstra, Barr RG, Burkart KM, A Manichaikul, TD Pottinger, EK Silverman, MH Cho, JD Crapo, TH Beaty, P Bakke, A Gulsvik, DA Lomas, Y Bossé, DC Nickle, PD Paré , HJ de Koning, JW Lammers, P Zanen, J Smolonska, C Wijmenga, CA Brandsma, HJ Groen, DS Postma
Eur Resp J,
2014, Jan;45(1):60-75. doi: 10.1183/09031936.00093314. Epub 2014 Sep 18
Expression and Regulation of CCR1 by Airway Smooth Muscle Cells in Asthma
P Joubert, S Lajoie-Kadoch, M Welman, S Dragon, S Létuvé, B Tolloczko, AJ Halayko, AS Gounni, K Maghni et Q Hamid
J. Immunol.,
2008, Jan 15; 180(2): 1268-75.
Genetic regulation of gene expression in the lung identifies CST3 and CD22 as potential causal genes for airflow obstruction
M Lamontagne, W Timens, K Hao, Y Bossé, M Laviolette, K Steiling, JD Campbell, C Couture, M Conti, K Sherwood, JC Hogg, CA Brandsma, M van den Berge, A Sandford, S Lam, ME Lenburg, A Spira, PD Paré, D Nickle, DD Sin, DS Postma
Thorax,
2014, Nov;69(11):997-1004. doi: 10.1136/thoraxjnl-2014-205630
Impact of Cigarette Smoke on the Human and Mouse Lungs: A Gene-Expression Comparison Study
MC Morissette, Lamontagne M, Bérubé JC, Gaschler G, Williams A, Yauk C, Couture C, Laviolette M, Hogg JC, Timens W, Halappanavar S, Stampfli MR, Bossé Y
PLoS ONE,
2014, Mar 24;9(3):e92498. doi: 10.1371/journal.pone.0092498. eCollection 2014
Impaired Angiogenesis and Peripheral Muscle Microcirculation Loss Contribute to Exercise Intolerance in Pulmonary Arterial Hypertension
F Potus, S Malenfant, C Graydon, V Mainguy, È Tremblay, S Breuils-Bonnet, F Ribeiro, A Porlier, F Maltais, S Bonnet, S Provencher
Am J Respir Crit Care Med,
2014, 2014 Aug 1;190(3):318-28. doi: 10.1164/rccm.201402-0383OC
Increased p53 level, Bax/Bcl-x(L) ratio, and TRAIL receptor expression in human emphysema.
MC Morissette, MC Morissette, G Vachon-Beaudoin, J Parent, J Chakir, J Milot.
Am J Respir Crit Care Med,
2008, Aug 1;178(3):240-7.
Increased T-cell survival by structural bronchial cells derived from asthmatic subjects cultured in an engineered human mucosa
ME Darveau, E Jacques, M Rouabhia, Q Hamid, J Chakir
J Allergy Clin Immun,
2008, Mar;121(3):692-9
Influence of smoking on airway inflammation and remodelling in asthma.
J St-Laurent, C Bergeron, N Pagé, C Couture, M Laviolette, LP Boulet
Clin. Exp. Allergy,
2008, Oct;38(10):1582-9.
Long-term pathologic consequences of acute irritant-induced asthma.
N Takeda, N Takeda, K Maghni, S Daigle, J L'Archevêque, L Castellanos, W Al-Ramli, JL Malo, Q Hamid.
J Allergy Clin Immun,
2009, Nov;124(5):975-81
MicroRNA-19a enhances proliferation of bronchial epithelial cells by targeting TGFβR2 gene in severe asthma
I Haj-Salem , R Fakhfakh, JC Bérubé, E Jacques, S Plante, MJ Simard, Y Bossé, J Chakir
Allergy, 2015, Feb;70(2):212-9. doi: 10.1111/all.12551
Myosin, transgelin, and myosin light chain kinase: expression and function in asthma.
R Léguillette, M Laviolette, C Bergeron, N Zitouni, P Kogut, J Solway , L Kachmar, Q Hamid et A-M Lauzon
Am J Respir Crit Care Med,
2009, 2009 Feb 1;179(3):194-204
Novel Genes for Airway Wall Thickness Identified with Combined Genome-Wide Association and Expression Analyses
AE Dijkstra , DS Postma , B van Ginneken,MO Wielpütz , M Schmidt, N Becker, M Owsijewitsch, HU Kauczor, HJ de Koning, JW Lammers, M Oudkerk , CA Brandsma, Y Bossé, DC Nickle, DD Sin, PS Hiemstra, C Wijmenga, J Smolonska, P Zanen , JM Vonk, M van den Berge, HM Boezen, HJ Groen
Am J Respir Crit Care Med,
2015, Mar 1;191(5):547-56. doi: 10.1164/rccm.201405-0840OC
Quality of bronchial biopsies for morphology study and cell sampling: a comparison of asthmatic and healthy subjects
I Labonté, M Laviolette, R Olivenstein , J Chakir, LP Boulet et Q Hamid
Can Resp J,
2008, Nov-Dec;15(8):431-5
Skeletal muscle proteomic signature and metabolic impairment in pulmonary hypertension
S Malenfant , F Potus, F Fournier, S Breuils-Bonnet, A Pflieger, S Bourassa, È Tremblay,B Nehmé, A Droit, S Bonnet, S Provencher
Journal of Molecular Medicine, 2014, Dec 30
Smooth Muscle in the Maintenance of Increased Airway Resistance Elicited by Methacholine in Humans
DG Chapman , CD Pascoe, A Lee-Gosselin,C Couture , CY Seow, PD Paré PD, CM Salome, GG King, Bossé Y
Am J Respir Cell Mol Biol,
2014, Oct 15;190(8):879-85. doi: 10.1164/rccm.201403-0502OC
Susceptibility loci for lung cancer are associated with mRNA levels of nearby genes in the lung
JD Nguyen, M Lamontagne, C Couture, M Conti, PD Paré, DD Sin, JC Hogg, D Nickle, DS Postma, W Timens, M Laviolette, Y Bossé
Carcinogenesis, 2014, Dec;35(12):2653-9. doi: 10.1093/carcin/bgu184
Susceptibility to Chronic Mucus Hypersecretion, a Genome Wide Association Study
AE Dijkstra, J Smolonska, M van den Berge, C Wijmenga, P Zanen, MA Luinge, M Platteel, JW Lammers, M Dahlback, K Tosh, PS Hiemstra, PJ Sterk, A Spira, J Vestbo, BG Nordestgaard, M Benn, SF Nielsen, M Dahl, WM Verschuren, HS Picavet, HA Smit, Owsijewitsch M, Kauczor HU, de Koning HJ, Nizankowska-Mogilnicka E, Mejza F, Nastalek P, van Diemen CC, Cho MH, Silverman EK, Crapo JD, Beaty TH, Lomas DA, Bakke P, Gulsvik A, Bossé Y, Obeidat MA, Loth DW, Lahousse L, Rivadeneira F, Uitterlinden AG, Hofman A, Stricker BH, Brusselle GG, van Duijn CM, Brouwer U, Koppelman GH, Vonk JM, Nawijn MC, Groen HJ, Timens W, Boezen HM, Postma DS
PLoS ONE,
2014, Apr 8;9(4):e91621. doi: 10.1371/journal.pone.0091621. eCollection 2014
Thymic stromal lymphopoietin-induced human asthmatic airway epithelial cell proliferation through an IL-13-dependent pathway.
A Semlali, E Jacques, L Koussih, AS Gounni, J Chakir.
J Allergy Clin Immun,
2010, Apr;125(4):844-50.
Tumor necrosis factor-alpha expression in uvular tissues differs between snorers and apneic patients.
L Loubaki, E Jacques, A Semlali, S Biardel, J Chakir, F Sériès
Chest,
2008, Nov;134(5):911-8.
Yin-Yang 1 regulates effector cytokine gene expression and T(H)2 immune responses
J Guo, X Lin, MA Williams, Q Hamid et SN Georas
J Allergy Clin Immun,
2008, Jul;122(1):195-201, 201.e1-5
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